在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOOK2 Antibody

HOOK2 Antibody

  • 中文名稱：
    HOOK2兔多克隆抗體
  • 貨號：
    CSB-PA839313ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: HOOK2 antibody at 4.11 μg/ml
      Lane 1: Mouse small intestine tissue
      Lane 2: A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83 kDa
      Observed band size: 83 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA839313ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA839313ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOOK2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOOK2
  • 別名：
    HOOK2 antibody; Protein Hook homolog 2 antibody; h-hook2 antibody; hHK2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Protein Hook homolog 2 protein (440-719AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
  • 基因功能參考文獻：
    1. We first demonstrate that Hook2 is essential for the polarized Golgi re-orientation towards the migration front. Depletion of Hook2 results in a decrease of PAR6alpha at the centrosome during cell migration, while overexpression of Hook2 in cells induced the formation of aggresomes with the recruitment of PAR6alpha, aPKC and PAR3 PMID: 27624926
    2. differential methylation profile of the HOOK2 gene in individuals with T2D and obesity might be related to the attendant T2D, but further studies are required to identify the potential role of HOOK2 gene in T2D disease PMID: 29228058
    3. Hook2 localizes at the Golgi apparatus and centrosome/basal body, a strategic partitioning for ciliogenesis. Hook2 interacts with PCM1. PMID: 21998199
    4. Results identify Hook2, a linker protein that is essential for regulation of the microtubule network at the centrosome, as a binding partner of CENP-F. PMID: 19793914
    5. Hook2 contributes to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes. PMID: 17540036

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Golgi apparatus, trans-Golgi network.
  • 蛋白家族：
    Hook family
  • 數據庫鏈接：

    HGNC: 19885

    OMIM: 607824

    KEGG: hsa:29911

    STRING: 9606.ENSP00000380785

    UniGene: Hs.30792



主站蜘蛛池模板： 少妇人妻中文字幕污| 久久久性色精品国产免费观看| 亚在线观看免费视频入口| 国产性猛交╳xxx乱大交| 中文文字幕文字幕亚洲色| 人妻老妇乱子伦精品无码专区| 又紧又黄的免费视频网站| 女人脱了内裤趴开腿让男躁| 美女视频黄是免费| 亚洲熟妇色xxxxx亚洲| 香港特级三a毛片免费观看| 女高中生自慰污污网站| 又大又硬又爽免费视频| 四虎影视成人永久免费观看视频 | 很色很爽很黄裸乳视频| 欧美亚洲日本国产综合在线| 日本19禁啪啪吃奶大尺度| 久久精品国产网红主播| 中文字幕乱码人妻一区二区三区 | 欧美日韩国产亚洲沙发| 强制高潮18xxxxhd日韩| 色狠狠成人综合网| 国产精品刮毛| 久久久久久人妻毛片a片| 大帝a∨无码视频在线播放| av小次郎收藏| 中文字幕乱码中文乱码777| 男女真人国产牲交a做片野外| 国产男女猛烈视频在线观看| 亲子乱子伦xxxx视频| 亚洲国产精品久久精品| 国产亚洲精品a在线| 亚洲腹肌男啪啪网站男同 | 99re6热视频这里只精品首页| 亚洲色欲在线播放一区| 国产精品免费看久久久无码 | 欧美18videosex性欧美黑吊| 精品一区二区不卡无码av| 久久超碰97人人做人人爱| 国产精品午夜视频自在拍| 熟女视频一区二区在线观看 |