在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HOOK2 Antibody

HOOK2 Antibody

  • 中文名稱：
    HOOK2兔多克隆抗體
  • 貨號：
    CSB-PA839313ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: HOOK2 antibody at 4.11 μg/ml
      Lane 1: Mouse small intestine tissue
      Lane 2: A431 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 83 kDa
      Observed band size: 83 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA839313ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA839313ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HOOK2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HOOK2
  • 別名：
    HOOK2 antibody; Protein Hook homolog 2 antibody; h-hook2 antibody; hHK2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Protein Hook homolog 2 protein (440-719AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.
  • 基因功能參考文獻：
    1. We first demonstrate that Hook2 is essential for the polarized Golgi re-orientation towards the migration front. Depletion of Hook2 results in a decrease of PAR6alpha at the centrosome during cell migration, while overexpression of Hook2 in cells induced the formation of aggresomes with the recruitment of PAR6alpha, aPKC and PAR3 PMID: 27624926
    2. differential methylation profile of the HOOK2 gene in individuals with T2D and obesity might be related to the attendant T2D, but further studies are required to identify the potential role of HOOK2 gene in T2D disease PMID: 29228058
    3. Hook2 localizes at the Golgi apparatus and centrosome/basal body, a strategic partitioning for ciliogenesis. Hook2 interacts with PCM1. PMID: 21998199
    4. Results identify Hook2, a linker protein that is essential for regulation of the microtubule network at the centrosome, as a binding partner of CENP-F. PMID: 19793914
    5. Hook2 contributes to the establishment and maintenance of the pericentrosomal localization of aggresomes by promoting the microtubule-based delivery of protein aggregates to pericentriolar aggresomes. PMID: 17540036

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Golgi apparatus, trans-Golgi network.
  • 蛋白家族：
    Hook family
  • 數據庫鏈接：

    HGNC: 19885

    OMIM: 607824

    KEGG: hsa:29911

    STRING: 9606.ENSP00000380785

    UniGene: Hs.30792



主站蜘蛛池模板： 天天综合网亚在线| 国产婷婷一区二区三区| 亚洲国产一卡2卡3卡4卡5公司| 欧美人成视频在线视频| 日本乱亲伦视频中文字幕| 无码人妻人妻经典| 99精品视频在线观看| 丁香五月婷激情综合第九色| 无码精品人妻一区二区三区av| 欧美综合天天夜夜久久| 99re热这里只有精品视频| 亚洲综合av色婷婷五月蜜臀| 国产中年熟女高潮大集合| 国产成人8x人在线视频软件| 最新亚洲中文av在线不卡| 国产精品一区二区久久国产| 香蕉久久久久久久av网站| 亚洲午夜成人精品无码app| 日本精品aⅴ一区二区三区| 欧美乱大交xxxxx潮喷l头像| 国产超碰人人爱被ios解锁| 亚洲一卡2卡三卡4卡国色天香| av无码免费永久在线观看| 2020无码专区人妻系列日韩| 99久久久无码国产精品动漫| 亚洲中文综合网五月俺也去| 欧美巨大巨粗黑人性aaaaaa| 大地资源中文第3页| 午夜无码一区二区三区在线| 精品人妻无码区二区三区| 中文字幕无线码| av中文无码乱人伦在线观看| 国产成人av大片在线观看| 少妇精品无码一区二区免费视频| 无尺码精品产品日韩| 久久久av男人的天堂| 高潮迭起av乳颜射后入| 成人影片一区免费观看| 人人模人人爽人人喊久久| 国产午夜草莓视频在线观看| 人人插人人插人人爽|